Isordil to imdur conversion

Imdur for CHF?

2023.12.02 03:49 awesomeqasim Imdur for CHF?

As we all know only Isordil (isosorbide dinitrate) is approved for CHF + hydralazine. Are you comfortable substituting IMDUR (isosorbide mononitate) which is only approved for angina for it instead? What do you do in regular clinical practice? Links to any studies or evidence either way is appreciated!
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2019.12.30 20:25 gintrux For NO theory, why not just try nitroglycerin? Angina medication specifically boosting nitric oxide

It seems the community is still looking to test the validity of NO theory and methods to increase it. There is a medication called Nitroglycerin specifically to do just that and it's used for treatment of angina. From wikipedia:
Nitroglycerin belongs to a group of drugs called nitrates, which includes many other nitrates like isosorbide dinitrate (Isordil) and isosorbide mononitrate (Imdur, Ismo, Monoket). These agents all exert their effect by being converted to nitric oxide in the body by mitochondrial aldehyde dehydrogenase (ALDH2), and nitric oxide is a potent natural vasodilator.
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2014.02.28 22:10 PillzPillzPillz Nitroglycerin Conversion

Hello,
Does anyone know the approximate conversion of Imdur to Nitro patch? Tried searching the literature, but didn't find anything.
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